When he did, it took 2.5 seconds on average, but sometimes much longer. When his goal was to guide the cursor from the center of the screen to a target on the perimeter, he hit the target 73 to 95 percent of the time. Nagle’s control of the computer cursor was not particularly smooth. Some of the paper’s other authors work at the company, while still others are from academic or medical institutions including Massachusetts General Hospital. Donoghue, the chief developer, is co-founder and chief scientist of Cyberkinetics. Surgenor, president and chief executive, said Cyberkinetics hoped to have an implant approved for marketing as early as 2008 or 2009. The company is now testing the system in three other people, who remain anonymous: one with a spinal cord injury, one with Lou Gehrig’s disease and one who had a brain stem stroke. The implant system, known as the BrainGate, is being developed by Cyberkinetics Neurotechnology Systems Inc. Nagle’s motor cortex were still active years after they had last had a role to play in moving his arms. Still, scientists said the study was particularly important because it showed that the neurons in Mr. Nagle required recalibration of the system each day, a task that took technicians about half an hour. In addition, the implant would ideally transmit signals wirelessly out of the brain, doing away with the permanent hole in the head and the accompanying risk of infection. For one thing, the electrodes’ ability to detect brain signals begins to deteriorate after several months, for reasons not fully understood.
Obstacles must be overcome, though, before brain implants become practical. Matthew Nagle, left paralyzed when he was stabbed five years ago, and the circle he drew on a computer screen by using only his thoughts. Nagle’s motor cortex responsible for arm movement and was connected to a pedestal that protruded from the top of his skull. The device was implanted in the area of Mr. The sensor measures 4 millimeters by 4 millimeters - less than a fifth of an inch long and wide - and contains 100 tiny electrodes.
Scott, professor of anatomy and cell biology at Queen’s University in Ontario, wrote in a commentary in the journal. The paper helps “shift the notion of such ‘implantable neuromotor prosthetics’ from science fiction towards reality,” Stephen H. Nagle has talked before about his experience.īut the paper in Nature is the first peer-reviewed publication of an experiment in people with a more sophisticated implant, able to monitor many more brain neurons than earlier devices. There have also been some tests of a simpler sensor implant in people, as well as systems using electrodes outside the scalp. Implants like the one he received had previously worked in monkeys. The man who stabbed him is now serving 10 years in prison, he said. He said he had not been involved in starting the brawl and did not even know what had sparked it.
Nagle, a former high school football star in Weymouth, Mass., was paralyzed below the shoulders after being stabbed in the neck during a melee at a beach in July 2001. He said the implant did not cause any pain. Nagle, 26, said in a telephone interview from the New England Sinai Hospital and Rehabilitation Center in Stoughton, Mass. “I pretty much had that mastered in four days,” Mr.
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